T Lymphocytes in Patients With Nijmegen Breakage Syndrome Demonstrate Features of Exhaustion and Senescence in Flow Cytometric Evaluation of Maturation Pathway

Patients with Nijmegen Breakage Syndrome (NBS) suffer from recurrent infections due to humoral and cellular immune deficiency. Despite low number of T lymphocytes and their maturation defect, the clinical manifestations of cell-mediated deficiency are not as severe as in case of patients with other...

Descripción completa

Detalles Bibliográficos
Autores principales: Piatosa, Barbara, Wolska-Kuśnierz, Beata, Tkaczyk, Katarzyna, Heropolitanska-Pliszka, Edyta, Grycuk, Urszula, Wakulinska, Anna, Gregorek, Hanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338427/
https://www.ncbi.nlm.nih.gov/pubmed/32695108
http://dx.doi.org/10.3389/fimmu.2020.01319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338427/
https://www.ncbi.nlm.nih.gov/pubmed/32695108
http://dx.doi.org/10.3389/fimmu.2020.01319

Ejemplares similares