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Activating PIK3CA mutation promotes osteogenesis of bone marrow mesenchymal stem cells in macrodactyly

Macrodactyly is a disabling congenital disease characterized by overgrowth of soft tissues and bones, which leads to finger enlargement and joint deformity. The mechanism of bone overgrowth in macrodactyly was rarely understood. In our study bone manifestations of three macrodactyly patients were an...

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Detalles Bibliográficos
Autores principales: Cui, Hengqing, Han, Gang, Sun, Bin, Fang, Xia, Dai, Xinyi, Zhou, Shengbo, Mao, Hailei, Wang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338441/
https://www.ncbi.nlm.nih.gov/pubmed/32632138
http://dx.doi.org/10.1038/s41419-020-2723-6