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Activating PIK3CA mutation promotes osteogenesis of bone marrow mesenchymal stem cells in macrodactyly
Macrodactyly is a disabling congenital disease characterized by overgrowth of soft tissues and bones, which leads to finger enlargement and joint deformity. The mechanism of bone overgrowth in macrodactyly was rarely understood. In our study bone manifestations of three macrodactyly patients were an...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338441/ https://www.ncbi.nlm.nih.gov/pubmed/32632138 http://dx.doi.org/10.1038/s41419-020-2723-6 |