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TIGAR/AP-1 axis accelerates the division of Lgr5(−) reserve intestinal stem cells to reestablish intestinal architecture after lethal radiation
During radiologic or nuclear accidents, high-dose ionizing radiation (IR) can cause gastrointestinal syndrome (GIS), a deadly disorder that urgently needs effective therapy. Unfortunately, current treatments based on natural products and antioxidants have shown very limited effects in alleviating de...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338449/ https://www.ncbi.nlm.nih.gov/pubmed/32632140 http://dx.doi.org/10.1038/s41419-020-2715-6 |