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TIGAR/AP-1 axis accelerates the division of Lgr5(−) reserve intestinal stem cells to reestablish intestinal architecture after lethal radiation

During radiologic or nuclear accidents, high-dose ionizing radiation (IR) can cause gastrointestinal syndrome (GIS), a deadly disorder that urgently needs effective therapy. Unfortunately, current treatments based on natural products and antioxidants have shown very limited effects in alleviating de...

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Detalles Bibliográficos
Autores principales:	Chen, Fei, Zhang, Yushuo, Hu, Songling, Shi, Xiaolin, Wang, Zhongmin, Deng, Zicheng, Lin, Longxin, Zhang, Jianghong, Pan, Yan, Bai, Yang, Liu, Fenju, Zhang, Haowen, Shao, Chunlin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338449/ https://www.ncbi.nlm.nih.gov/pubmed/32632140 http://dx.doi.org/10.1038/s41419-020-2715-6

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