Targeting focal adhesion kinase in cancer cells and the tumor microenvironment

Focal adhesion kinase (FAK) is an integrin-associated protein tyrosine kinase that is frequently overexpressed in advanced human cancers. Recent studies have demonstrated that aside from FAK’s catalytic activity in cancer cells, its cellular localization is also critical for regulating the transcrip...

Descripción completa

Detalles Bibliográficos
Autores principales: Murphy, James M., Rodriguez, Yelitza A. R., Jeong, Kyuho, Ahn, Eun-Young Erin, Lim, Ssang-Taek Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338452/
https://www.ncbi.nlm.nih.gov/pubmed/32514188
http://dx.doi.org/10.1038/s12276-020-0447-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338452/
https://www.ncbi.nlm.nih.gov/pubmed/32514188
http://dx.doi.org/10.1038/s12276-020-0447-4

Ejemplares similares