Genetic reduction of the extracellular matrix protein versican attenuates inflammatory cell infiltration and improves contractile function in dystrophic mdx diaphragm muscles

There is a persistent, aberrant accumulation of V0/V1 versican in skeletal muscles from patients with Duchenne muscular dystrophy and in diaphragm muscles from mdx mice. Versican is a provisional matrix protein implicated in fibrosis and inflammation in various disease states, yet its role in the pa...

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Detalles Bibliográficos
Autores principales: McRae, Natasha L., Addinsall, Alex B., Howlett, Kirsten F., McNeill, Bryony, McCulloch, Daniel R., Stupka, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338466/
https://www.ncbi.nlm.nih.gov/pubmed/32632164
http://dx.doi.org/10.1038/s41598-020-67464-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338466/
https://www.ncbi.nlm.nih.gov/pubmed/32632164
http://dx.doi.org/10.1038/s41598-020-67464-x

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