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Insulin receptor endocytosis in the pathophysiology of insulin resistance

Insulin signaling controls cell growth and metabolic homeostasis. Dysregulation of this pathway causes metabolic diseases such as diabetes. Insulin signaling pathways have been extensively studied. Upon insulin binding, the insulin receptor (IR) triggers downstream signaling cascades. The active IR...

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Detalles Bibliográficos
Autores principales: Hall, Catherine, Yu, Hongtao, Choi, Eunhee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338473/
https://www.ncbi.nlm.nih.gov/pubmed/32576931
http://dx.doi.org/10.1038/s12276-020-0456-3