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A Novel Cecropin-LL37 Hybrid Peptide Protects Mice Against EHEC Infection-Mediated Changes in Gut Microbiota, Intestinal Inflammation, and Impairment of Mucosal Barrier Functions

Intestinal inflammation can cause impaired epithelial barrier function and disrupt immune homeostasis, which increases the risks of developing many highly fatal diseases. Enterohemorrhagic Escherichia coli (EHEC) O157:H7 causes intestinal infections worldwide and is a major pathogen that induces int...

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Detalles Bibliográficos
Autores principales: Wei, Xubiao, Zhang, Lulu, Zhang, Rijun, Koci, Matthew, Si, Dayong, Ahmad, Baseer, Cheng, Junhao, Wang, Junyong, Aihemaiti, Maierhaba, Zhang, Manyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338479/
https://www.ncbi.nlm.nih.gov/pubmed/32695115
http://dx.doi.org/10.3389/fimmu.2020.01361