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Heterologous Chimeric Construct Comprising a Modified Bacterial Superantigen and a Cruzipain Domain Confers Protection Against Trypanosoma cruzi Infection

Chagas disease is an endemic chronic parasitosis in Latin America affecting more than 7 million people. Around 100 million people are currently at risk of acquiring the infection; however, no effective vaccine has been developed yet. Trypanosoma cruzi is the etiological agent of this parasitosis and...

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Detalles Bibliográficos
Autores principales: Antonoglou, María Belén, Sánchez Alberti, Andrés, Redolfi, Daniela María, Bivona, Augusto Ernesto, Fernández Lynch, María Julieta, Noli Truant, Sofía, Sarratea, María Belén, Iannantuono López, Laura Valeria, Malchiodi, Emilio Luis, Fernández, Marisa Mariel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338481/
https://www.ncbi.nlm.nih.gov/pubmed/32695105
http://dx.doi.org/10.3389/fimmu.2020.01279