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Upregulated TRAIL and Reduced DcR2 Mediate Apoptosis of Decidual PMN-MDSC in Unexplained Recurrent Pregnancy Loss

Myeloid-derived suppressor cells (MDSC), especially polymorphonuclear MDSC (PMN-MDSC), accumulate in maternal-fetal interface during pregnancy and are involved in the maintenance of immune tolerance. Decreased PMN-MDSC is associated with pregnancy complications such as unexplained recurrent pregnanc...

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Detalles Bibliográficos
Autores principales: Li, Congcong, Zhang, Xiaoxin, Kang, Xiaomin, Chen, Chao, Guo, Feng, Wang, Qiaohong, Zhao, Aimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338483/
https://www.ncbi.nlm.nih.gov/pubmed/32695113
http://dx.doi.org/10.3389/fimmu.2020.01345