TGR5-HNF4α axis contributes to bile acid-induced gastric intestinal metaplasia markers expression

Intestinal metaplasia (IM) increases the risk of gastric cancer. Our previous results indicated that bile acids (BAs) reflux promotes gastric IM development through kruppel-like factor 4 (KLF4) and caudal-type homeobox 2 (CDX2) activation. However, the underlying mechanisms remain largely elusive. H...

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Detalles Bibliográficos
Autores principales: Ni, Zhen, Min, Yali, Han, Chuan, Yuan, Ting, Lu, Wenquan, Ashktorab, Hassan, Smoot, Duane T., Wu, Qiong, Wu, Jian, Zeng, Weizheng, Shi, Yongquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338499/
https://www.ncbi.nlm.nih.gov/pubmed/32655894
http://dx.doi.org/10.1038/s41420-020-0290-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338499/
https://www.ncbi.nlm.nih.gov/pubmed/32655894
http://dx.doi.org/10.1038/s41420-020-0290-3

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