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Flightless-1 inhibits ER stress-induced apoptosis in colorectal cancer cells by regulating Ca(2+) homeostasis

The endoplasmic reticulum (ER) stress response is an adaptive mechanism that is activated upon disruption of ER homeostasis and protects the cells against certain harmful environmental stimuli. However, critical and prolonged cell stress triggers cell death. In this study, we demonstrate that Flight...

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Detalles Bibliográficos
Autores principales: Choi, Sun Sil, Lee, Sang Kwon, Kim, Joong Kwan, Park, Hye-Kyung, Lee, Eujin, Jang, Jinho, Lee, Yo Han, Khim, Keon Woo, Hyun, Ji-Min, Eom, Hye-jin, Lee, Semin, Kang, Byuong Heon, Chae, Young Chan, Myung, Kyungjae, Myung, Seung-Jae, Park, Chan Young, Choi, Jang Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338537/
https://www.ncbi.nlm.nih.gov/pubmed/32504039
http://dx.doi.org/10.1038/s12276-020-0448-3