A Brain-Penetrating Hsp90 Inhibitor NXD30001 Inhibits Glioblastoma as a Monotherapy or in Combination With Radiation

Glioblastoma multiforme (GBM) is a highly heterogeneous disease, which is initiated and sustained by various molecular alterations in an array of signal transduction pathways. Heat-shock protein 90 (Hsp90) is a molecular chaperone and is critically implicated in folding and activation of a diverse g...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Hao, Gong, Yuanying, Ma, Yufang, Thompson, Reid C., Wang, Jialiang, Cheng, Zhixiang, Xue, Lixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338553/
https://www.ncbi.nlm.nih.gov/pubmed/32695001
http://dx.doi.org/10.3389/fphar.2020.00974

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338553/
https://www.ncbi.nlm.nih.gov/pubmed/32695001
http://dx.doi.org/10.3389/fphar.2020.00974

Ejemplares similares