Long-Term Inhibition of Notch in A-375 Melanoma Cells Enhances Tumor Growth Through the Enhancement of AXIN1, CSNK2A3, and CEBPA2 as Intermediate Genes in Wnt and Notch Pathways

Notch suppression by gamma-secretase inhibitors is a valid approach against melanoma. However, most of studies have evaluated the short-term effect of DAPT on tumor cells or even cancer stem cells. In the present study, we surveyed the short-term and long-term effects of DAPT on the stem cell proper...

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Detalles Bibliográficos
Autores principales: Keyghobadi, Faezeh, Mehdipour, Maryam, Nekoukar, Vahab, Firouzi, Javad, Kheimeh, Abolfazl, Nobakht Lahrood, Fatemeh, Azimian Zavareh, Vajihe, Azimi, Masoumeh, Mohammadi, Mahsa, Sodeifi, Niloofar, Ebrahimi, Marzieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338939/
https://www.ncbi.nlm.nih.gov/pubmed/32695658
http://dx.doi.org/10.3389/fonc.2020.00531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338939/
https://www.ncbi.nlm.nih.gov/pubmed/32695658
http://dx.doi.org/10.3389/fonc.2020.00531

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