Cargando…

Tmub1 Suppresses Hepatocellular Carcinoma by Promoting the Ubiquitination of ΔNp63 Isoforms

Transmembrane and ubiquitin-like domain-containing 1 (Tmub1) inhibits hepatocyte proliferation during liver regeneration, but its role in hepatocellular carcinoma (HCC) has yet to be revealed. In this study, we show that the levels of Tmub1 were significantly lower in HCC tissues and cells than they...

Descripción completa

Detalles Bibliográficos
Autores principales: Fu, Hangwei, Zhang, Yida, Chen, Junying, Zhou, Bo, Chen, Geng, Chen, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338996/
https://www.ncbi.nlm.nih.gov/pubmed/32671188
http://dx.doi.org/10.1016/j.omto.2020.06.005