Antibodies to the Muscarinic Acetylcholine Receptor M3 in Primary Biliary Cholangitis Inhibit Receptor Function on Cholangiocytes

Background and Aims: In primary biliary cholangitis (PBC), antibodies to a peptide of the muscarinic acetylcholine receptor 3 (mAChR3) have been described. Since the mAChR3 is expressed on cholangiocytes and mAChR3-signaling is involved in the pathogenesis of chronic inflammatory biliary diseases, w...

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Detalles Bibliográficos
Autores principales: Mayer, Christian, Preuss, Beate, Grottenthaler, Julia, Berg, Christoph, Klein, Reinhild
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339122/
https://www.ncbi.nlm.nih.gov/pubmed/32695096
http://dx.doi.org/10.3389/fimmu.2020.01151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339122/
https://www.ncbi.nlm.nih.gov/pubmed/32695096
http://dx.doi.org/10.3389/fimmu.2020.01151

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