The GDF‐5 mutant M1673 exerts robust anabolic and anti‐catabolic effects in chondrocytes

The growth and differentiation factor 5 (GDF‐5) is known to play a key role in cartilage morphogenesis and homeostasis, and a single‐nucleotide polymorphism in its promoter sequence was found to be associated with osteoarthritis (OA). In addition, GDF‐5 was shown to promote extracellular matrix (ECM...

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Detalles Bibliográficos
Autores principales: Mang, Tanja, Kleinschmidt‐Dörr, Kerstin, Ploeger, Frank, Lindemann, Sven, Gigout, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339174/
https://www.ncbi.nlm.nih.gov/pubmed/32497388
http://dx.doi.org/10.1111/jcmm.15149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339174/
https://www.ncbi.nlm.nih.gov/pubmed/32497388
http://dx.doi.org/10.1111/jcmm.15149

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