AT2R agonist NP‐6A4 mitigates aortic stiffness and proteolytic activity in mouse model of aneurysm

Clinical and experimental studies show that angiotensin II (AngII) promotes vascular pathology via activation of AngII type 1 receptors (AT1Rs). We recently reported that NP‐6A4, a selective peptide agonist for AngII type 2 receptor (AT2R), exerts protective effects on human vascular cells subjected...

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Detalles Bibliográficos
Autores principales: Sharma, Neekun, Belenchia, Anthony M., Toedebusch, Ryan, Pulakat, Lakshmi, Hans, Chetan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339180/
https://www.ncbi.nlm.nih.gov/pubmed/32420690
http://dx.doi.org/10.1111/jcmm.15342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339180/
https://www.ncbi.nlm.nih.gov/pubmed/32420690
http://dx.doi.org/10.1111/jcmm.15342

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