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CFTR promotes malignant glioma development via up‐regulation of Akt/Bcl2‐mediated anti‐apoptosis pathway

Cystic fibrosis transmembrane conductance regulator (CFTR), a cAMP‐activated Cl(‐) channel, is extensively expressed in the epithelial cells of various tissues and organs. Accumulating evidence indicates that aberrant expression or mutation of CFTR is related to carcinoma development. Malignant glio...

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Detalles Bibliográficos
Autores principales: Zhao, Mingyue, Zhang, Jieting, Huang, Wenqing, Dong, Jianda, Guo, Jinghui, U, Kin Pong, Weng, ZhiHui, Liu, Si, Chan, Hsiao Chang, Feng, Hua, Jiang, Xiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339181/
https://www.ncbi.nlm.nih.gov/pubmed/32463592
http://dx.doi.org/10.1111/jcmm.15300