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CMap analysis identifies Atractyloside as a potential drug candidate for type 2 diabetes based on integration of metabolomics and transcriptomics

BACKGROUND: This research aimed at exploring the mechanisms of alterations of metabolites and pathways in T2D from the perspective of metabolomics and transcriptomics, as well as uncovering novel drug candidate for T2D treatment. METHODS: Metabolites in human plasma from 42 T2D patients and 45 non‐d...

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Detalles Bibliográficos
Autores principales: Li, Hailong, Shi, Xiaodong, Jiang, Hua, Kang, Junren, Yu, Miao, Li, Qifei, Yu, Kang, Chen, Zhengju, Pan, Hui, Chen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339182/
https://www.ncbi.nlm.nih.gov/pubmed/32469143
http://dx.doi.org/10.1111/jcmm.15357