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FLT3‐ITD DNA and mRNA levels in AML do not correlate with CD7, CD33 and CD123 expression

INTRODUCTION: FLT3 internal tandem duplication (ITD) mutations are found in around 25% of all acute myeloid leukaemia (AML) cases and is associated with shorter disease‐free and overall survival. Previous reports have shown that FLT3‐ITD induces a specific phenotype in leukemic blasts, which is char...

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Detalles Bibliográficos
Autores principales: Soare, Dan‐Sebastian, Radu, Eugen, Dumitru, Ion, Popov, Viola Maria, Bumbea, Horia, Vlădăreanu, Ana Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339186/
https://www.ncbi.nlm.nih.gov/pubmed/32460405
http://dx.doi.org/10.1111/jcmm.15255