Cargando…
Progress in the research of p53 tumour suppressor activity controlled by Numb in triple‐negative breast cancer
Numb is known as a cell fate determinant as it identifies the direction of cell differentiation via asymmetrical partitioning during mitosis. It is considered as a tumour suppressor, and a frequent loss of Numb expression in breast cancer is noted. Numb forms a tri‐complex with p53 and E3 ubiquitin...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339219/ https://www.ncbi.nlm.nih.gov/pubmed/32501652 http://dx.doi.org/10.1111/jcmm.15366 |