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MicroRNA‐708 modulates Hepatic Stellate Cells activation and enhances extracellular matrix accumulation via direct targeting TMEM88

Transmembrane protein 88 (TMEM88) is a potential 2‐transmembrane‐type protein that interacts with the PDZ domain of Dishevelled‐1 (DVL‐1), a crucial component of Wnt signalling pathway through its C‐terminal Val‐Trp‐Val (VWV) motif in Xenopus embryo cells. Since the significant function of β‐catenin...

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Detalles Bibliográficos
Autores principales: Xu, Tao, Pan, Linxin, Li, Liangyun, Hu, Shuang, Zhou, Hong, Yang, Chenchen, Yang, Junfa, Li, Haodong, Liu, Yuming, Meng, Xiaoming, Li, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339227/
https://www.ncbi.nlm.nih.gov/pubmed/32463570
http://dx.doi.org/10.1111/jcmm.15119