Dysregulation of cancer genes by recurrent intergenic fusions

BACKGROUND: Gene fusions have been studied extensively, as frequent drivers of tumorigenesis as well as potential therapeutic targets. In many well-known cases, breakpoints occur at two intragenic positions, leading to in-frame gene-gene fusions that generate chimeric mRNAs. However, fusions often o...

Descripción completa

Detalles Bibliográficos
Autores principales: Yun, Jae Won, Yang, Lixing, Park, Hye-Young, Lee, Chang-Woo, Cha, Hongui, Shin, Hyun-Tae, Noh, Ka-Won, Choi, Yoon-La, Park, Woong-Yang, Park, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339451/
https://www.ncbi.nlm.nih.gov/pubmed/32631391
http://dx.doi.org/10.1186/s13059-020-02076-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339451/
https://www.ncbi.nlm.nih.gov/pubmed/32631391
http://dx.doi.org/10.1186/s13059-020-02076-2

Ejemplares similares