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Dysregulation of cancer genes by recurrent intergenic fusions

BACKGROUND: Gene fusions have been studied extensively, as frequent drivers of tumorigenesis as well as potential therapeutic targets. In many well-known cases, breakpoints occur at two intragenic positions, leading to in-frame gene-gene fusions that generate chimeric mRNAs. However, fusions often o...

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Detalles Bibliográficos
Autores principales:	Yun, Jae Won, Yang, Lixing, Park, Hye-Young, Lee, Chang-Woo, Cha, Hongui, Shin, Hyun-Tae, Noh, Ka-Won, Choi, Yoon-La, Park, Woong-Yang, Park, Peter J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339451/ https://www.ncbi.nlm.nih.gov/pubmed/32631391 http://dx.doi.org/10.1186/s13059-020-02076-2

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