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TNF-α treatment increases DKK1 protein levels in primary osteoblasts via upregulation of DKK1 mRNA levels and downregulation of miR-335-5p

Elucidation of the underlying mechanisms governing osteogenic differentiation is of significant importance to the improvement of therapeutics for bone-related inflammatory diseases. Tumor necrosis factor-α (TNF-α) is regarded as one of the major agents during osteogenic differentiation in an inflamm...

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Detalles Bibliográficos
Autores principales: Li, Shanshan, Yin, Yixin, Yao, Liping, Lin, Ziyi, Sun, Shengjun, Zhang, Jin, Li, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339467/
https://www.ncbi.nlm.nih.gov/pubmed/32468044
http://dx.doi.org/10.3892/mmr.2020.11152