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TNF-α treatment increases DKK1 protein levels in primary osteoblasts via upregulation of DKK1 mRNA levels and downregulation of miR-335-5p
Elucidation of the underlying mechanisms governing osteogenic differentiation is of significant importance to the improvement of therapeutics for bone-related inflammatory diseases. Tumor necrosis factor-α (TNF-α) is regarded as one of the major agents during osteogenic differentiation in an inflamm...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339467/ https://www.ncbi.nlm.nih.gov/pubmed/32468044 http://dx.doi.org/10.3892/mmr.2020.11152 |