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Variations in Trim5α and Cyclophilin A genes among HIV-1 elite controllers and non controllers in Uganda: a laboratory-based cross-sectional study

BACKGROUND: Tripartite Motif Containing 5 alpha (TRIM5α), a restriction factor produced ubiquitously in cells and tissues of the body plays an important role in the immune response against HIV. TRIM5α targets the HIV capsid for proteosomal destruction. Cyclophilin A, an intracellular protein has als...

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Detalles Bibliográficos
Autores principales: Amanya, Sharon Bright, Nyiro, Brian, Waswa, Francis, Obura, Bonniface, Nakaziba, Rebecca, Nabulime, Eva, Katabazi, Ashaba Fred, Nabatanzi, Rose, Bayiyana, Alice, Mboowa, Gerald, Kayongo, Alex, Wayengera, Misaki, Sande, Obondo J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339491/
https://www.ncbi.nlm.nih.gov/pubmed/32631377
http://dx.doi.org/10.1186/s12977-020-00527-z