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Hypoxia, metabolism, and the circadian clock: new links to overcome radiation resistance in high-grade gliomas
Radiotherapy is the cornerstone of treatment of high-grade gliomas (HGGs). It eradicates tumor cells by inducing oxidative stress and subsequent DNA damage. Unfortunately, almost all HGGs recur locally within several months secondary to radioresistance with intricate molecular mechanisms. Therefore,...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339573/ https://www.ncbi.nlm.nih.gov/pubmed/32631383 http://dx.doi.org/10.1186/s13046-020-01639-2 |