Identification of geraldol as an inhibitor of aquaporin-4 binding by NMO-IgG

Neuromyelitis optica (NMO) is a severe neurological demyelinating autoimmune disease that affects the optic nerves and spinal cord. There is currently no effective cure or therapy. Aquaporin-4 (AQP4) is a known target of the autoimmune antibody NMO-IgG. Therefore, binding of NMO-IgG to AQP4, and sub...

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Detalles Bibliográficos
Autores principales: Wang, Jie, Wang, Shuai, Sun, Meiyan, Xu, Huijing, Liu, Wei, Wang, Deli, Zhang, Lei, Li, Yan, Cao, Jiaming, Li, Fang, Li, Miao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339707/
https://www.ncbi.nlm.nih.gov/pubmed/32626958
http://dx.doi.org/10.3892/mmr.2020.11212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339707/
https://www.ncbi.nlm.nih.gov/pubmed/32626958
http://dx.doi.org/10.3892/mmr.2020.11212

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