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Identification of geraldol as an inhibitor of aquaporin-4 binding by NMO-IgG
Neuromyelitis optica (NMO) is a severe neurological demyelinating autoimmune disease that affects the optic nerves and spinal cord. There is currently no effective cure or therapy. Aquaporin-4 (AQP4) is a known target of the autoimmune antibody NMO-IgG. Therefore, binding of NMO-IgG to AQP4, and sub...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339707/ https://www.ncbi.nlm.nih.gov/pubmed/32626958 http://dx.doi.org/10.3892/mmr.2020.11212 |