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SAMHD1 expression is associated with low immune activation but not correlated with HIV-1 DNA levels in CD4(+) T cells of patients with HIV-1

Sterile α motif and histidine/aspartic acid domain-containing protein 1 (SAMHD1) can inhibit reverse transcription of human immunodeficiency virus-1 (HIV-1) by hydrolyzing intracellular deoxy-ribonucleoside triphosphate. However, its role in HIV-1 disease progression has not been extensively studied...

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Detalles Bibliográficos
Autores principales: Li, Jie, Gao, Chuanhua, Huang, Shanshan, Jin, Longteng, Jin, Changzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339818/
https://www.ncbi.nlm.nih.gov/pubmed/32468062
http://dx.doi.org/10.3892/mmr.2020.11153