A helical assembly of human ESCRT-I scaffolds reverse-topology membrane scission

The ESCRT complexes drive membrane scission in HIV-1 release, autophagosome closure, MVB biogenesis, cytokinesis, and other cell processes. ESCRT-I is the most upstream complex and bridges the system to HIV-1 Gag in virus release. The crystal structure of the headpiece of human ESCRT-I comprising TS...

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Detalles Bibliográficos
Autores principales: Flower, Thomas G., Takahashi, Yoshinori, Hudait, Arpa, Rose, Kevin, Tjahjono, Nicholas, Pak, Alexander J., Yokom, Adam L., Liang, Xinwen, Wang, Hong-Gang, Bouamr, Fadila, Voth, Gregory A., Hurley, James H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339825/
https://www.ncbi.nlm.nih.gov/pubmed/32424346
http://dx.doi.org/10.1038/s41594-020-0426-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339825/
https://www.ncbi.nlm.nih.gov/pubmed/32424346
http://dx.doi.org/10.1038/s41594-020-0426-4

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