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Construction of a Stable and Temperature-Responsive Yeast Cell Factory for Crocetin Biosynthesis Using CRISPR-Cas9

Crocetin is a plant natural product with broad medicinal applications, such as improvement of sleep quality and attenuation of physical fatigue. However, crocetin production using microbial cell factories is still far from satisfaction, probably due to the conflict between cell growth and product ac...

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Detalles Bibliográficos
Autores principales: Liu, Tengfei, Dong, Chang, Qi, Mingming, Zhang, Bei, Huang, Lei, Xu, Zhinan, Lian, Jiazhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339864/
https://www.ncbi.nlm.nih.gov/pubmed/32695754
http://dx.doi.org/10.3389/fbioe.2020.00653