Translocator Protein 18 kDa (TSPO) Deficiency Inhibits Microglial Activation and Impairs Mitochondrial Function

TSPO is mainly expressed in the mitochondrial outer membrane of microglia in the central nervous system, and its expression is greatly increased when microglia are activated. However, the role and mechanism of this protein in microglial activation is not well characterized. In this study, we investi...

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Detalles Bibliográficos
Autores principales: Yao, Rumeng, Pan, Ruiyuan, Shang, Chao, Li, Xiaoheng, Cheng, Jinbo, Xu, Jiangping, Li, Yunfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339871/
https://www.ncbi.nlm.nih.gov/pubmed/32695005
http://dx.doi.org/10.3389/fphar.2020.00986

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339871/
https://www.ncbi.nlm.nih.gov/pubmed/32695005
http://dx.doi.org/10.3389/fphar.2020.00986

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