Inhibition of Oxidative Phosphorylation Reverses Bone Marrow Hypoxia Visualized in Imageable Syngeneic B-ALL Mouse Model

Abnormally low level of interstitial oxygen, or hypoxia, is a hallmark of tumor microenvironment and a known promoter of cancer chemoresistance. Inside a solid tumor mass, the hypoxia stems largely from inadequate supply of oxygenated blood through sparse or misshapen tumor vasculature whilst oxygen...

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Detalles Bibliográficos
Autores principales: Rytelewski, Mateusz, Harutyunyan, Karine, Baran, Natalia, Mallampati, Saradhi, Zal, M. Anna, Cavazos, Antonio, Butler, Jason M., Konoplev, Sergej, El Khatib, Mirna, Plunkett, Shane, Marszalek, Joseph R., Andreeff, Michael, Zal, Tomasz, Konopleva, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339962/
https://www.ncbi.nlm.nih.gov/pubmed/32695673
http://dx.doi.org/10.3389/fonc.2020.00991

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339962/
https://www.ncbi.nlm.nih.gov/pubmed/32695673
http://dx.doi.org/10.3389/fonc.2020.00991

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