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Inhibition of M/K(v)7 Currents Contributes to Chloroquine-Induced Itch in Mice

M/K(v)7 potassium channels play a key role in regulation of neuronal excitability. Modulation of neuronal excitability of primary sensory neurons determines the itch sensation induced by a variety of itch-causing substances including chloroquine (CQ). In the present study, we demonstrate that suppre...

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Detalles Bibliográficos
Autores principales: Zhang, Dong, Men, Hongchao, Zhang, Ludi, Gao, Xiangxin, Wang, Jingjing, Li, Leying, Zhu, Qiaoying, Zhang, Hailin, Jia, Zhanfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339983/
https://www.ncbi.nlm.nih.gov/pubmed/32694980
http://dx.doi.org/10.3389/fnmol.2020.00105