Impute.me: An Open-Source, Non-profit Tool for Using Data From Direct-to-Consumer Genetic Testing to Calculate and Interpret Polygenic Risk Scores

To date, interpretation of genomic information has focused on single variants conferring disease risk, but most disorders of major public concern have a polygenic architecture. Polygenic risk scores (PRSs) give a single measure of disease liability by summarizing disease risk across hundreds of thou...

Descripción completa

Detalles Bibliográficos
Autores principales: Folkersen, Lasse, Pain, Oliver, Ingason, Andrés, Werge, Thomas, Lewis, Cathryn M., Austin, Jehannine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340159/
https://www.ncbi.nlm.nih.gov/pubmed/32714365
http://dx.doi.org/10.3389/fgene.2020.00578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340159/
https://www.ncbi.nlm.nih.gov/pubmed/32714365
http://dx.doi.org/10.3389/fgene.2020.00578

Ejemplares similares