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P2X7 Receptors as a Therapeutic Target in Cerebrovascular Diseases

Shortage of oxygen and nutrients in the brain induces the release of glutamate and ATP that can cause excitotoxicity and contribute to neuronal and glial damage. Our understanding of the mechanisms of ATP release and toxicity in cerebrovascular diseases is incomplete. This review aims at summarizing...

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Detalles Bibliográficos
Autores principales: Cisneros-Mejorado, Abraham J., Pérez-Samartín, Alberto, Domercq, María, Arellano, Rogelio O., Gottlieb, Miroslav, Koch-Nolte, Friedrich, Matute, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340211/
https://www.ncbi.nlm.nih.gov/pubmed/32714144
http://dx.doi.org/10.3389/fnmol.2020.00092