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Structure-based screening of binding affinities via small-angle X-ray scattering

Protein–protein and protein–ligand interactions often involve conformational changes or structural rearrangements that can be quantified by solution small-angle X-ray scattering (SAXS). These scattering intensity measurements reveal structural details of the bound complex, the number of species invo...

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Detalles Bibliográficos
Autores principales: Chen, Po-chia, Masiewicz, Pawel, Perez, Kathryn, Hennig, Janosch
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340254/
https://www.ncbi.nlm.nih.gov/pubmed/32695411
http://dx.doi.org/10.1107/S2052252520004169