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Structure-based screening of binding affinities via small-angle X-ray scattering
Protein–protein and protein–ligand interactions often involve conformational changes or structural rearrangements that can be quantified by solution small-angle X-ray scattering (SAXS). These scattering intensity measurements reveal structural details of the bound complex, the number of species invo...
Autores principales: | Chen, Po-chia, Masiewicz, Pawel, Perez, Kathryn, Hennig, Janosch |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340254/ https://www.ncbi.nlm.nih.gov/pubmed/32695411 http://dx.doi.org/10.1107/S2052252520004169 |
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