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Structural basis of self-assembly in the lipid-binding domain of mycobacterial polar growth factor Wag31

Wag31, or DivIVA, is an essential protein and a drug target in the human pathogen Mycobacterium tuberculosis that self-assembles at the negatively curved membrane surface to form a higher-order structural scaffold, maintains rod-shaped cellular morphology and localizes key cell-wall synthesizing enz...

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Detalles Bibliográficos
Autores principales: Choukate, Komal, Chaudhuri, Barnali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340271/
https://www.ncbi.nlm.nih.gov/pubmed/32695423
http://dx.doi.org/10.1107/S2052252520006053