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Structural basis of self-assembly in the lipid-binding domain of mycobacterial polar growth factor Wag31
Wag31, or DivIVA, is an essential protein and a drug target in the human pathogen Mycobacterium tuberculosis that self-assembles at the negatively curved membrane surface to form a higher-order structural scaffold, maintains rod-shaped cellular morphology and localizes key cell-wall synthesizing enz...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340271/ https://www.ncbi.nlm.nih.gov/pubmed/32695423 http://dx.doi.org/10.1107/S2052252520006053 |