Tn-Seq reveals hidden complexity in the utilization of host-derived glutathione in Francisella tularensis

Host-derived glutathione (GSH) is an essential source of cysteine for the intracellular pathogen Francisella tularensis. In a comprehensive transposon insertion sequencing screen, we identified several F. tularensis genes that play central and previously unappreciated roles in the utilization of GSH...

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Detalles Bibliográficos
Autores principales: Ramsey, Kathryn M., Ledvina, Hannah E., Tresko, Tenayaann M., Wandzilak, Jamie M., Tower, Catherine A., Tallo, Thomas, Schramm, Caroline E., Peterson, S. Brook, Skerrett, Shawn J., Mougous, Joseph D., Dove, Simon L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340319/
https://www.ncbi.nlm.nih.gov/pubmed/32492066
http://dx.doi.org/10.1371/journal.ppat.1008566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340319/
https://www.ncbi.nlm.nih.gov/pubmed/32492066
http://dx.doi.org/10.1371/journal.ppat.1008566

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