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Tn-Seq reveals hidden complexity in the utilization of host-derived glutathione in Francisella tularensis
Host-derived glutathione (GSH) is an essential source of cysteine for the intracellular pathogen Francisella tularensis. In a comprehensive transposon insertion sequencing screen, we identified several F. tularensis genes that play central and previously unappreciated roles in the utilization of GSH...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340319/ https://www.ncbi.nlm.nih.gov/pubmed/32492066 http://dx.doi.org/10.1371/journal.ppat.1008566 |