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The mTORC2 Component Rictor Is Required for Load‐Induced Bone Formation in Late‐Stage Skeletal Cells

Bone relies on mechanical cues to build and maintain tissue composition and architecture. Our understanding of bone cell mechanotransduction continues to evolve, with a few key signaling pathways emerging as vital. Wnt/β‐catenin, for example, is essential for proper anabolic response to mechanical s...

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Detalles Bibliográficos
Autores principales: Lewis, Karl J, Yi, Xin, Wright, Christian S, Pemberton, Emily Z, Bullock, Whitney A, Thompson, William R, Robling, Alexander G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340445/
https://www.ncbi.nlm.nih.gov/pubmed/32666017
http://dx.doi.org/10.1002/jbm4.10366