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Aberrant sorting of hippocampal complex pyramidal cells in type I lissencephaly alters topological innervation

Layering has been a long-appreciated feature of higher order mammalian brain structures but the extent to which it plays an instructive role in synaptic specification remains unknown. Here we examine the formation of synaptic circuitry under cellular heterotopia in hippocampal CA1, using a mouse mod...

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Detalles Bibliográficos
Autores principales: D'Amour, James A, Ekins, Tyler, Ganatra, Stuti, Yuan, Xiaoqing, McBain, Chris J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340499/
https://www.ncbi.nlm.nih.gov/pubmed/32558643
http://dx.doi.org/10.7554/eLife.55173