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The Wg and Dpp morphogens regulate gene expression by modulating the frequency of transcriptional bursts

Morphogen signaling contributes to the patterned spatiotemporal expression of genes during development. One mode of regulation of signaling-responsive genes is at the level of transcription. Single-cell quantitative studies of transcription have revealed that transcription occurs intermittently, in...

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Detalles Bibliográficos
Autores principales: Bakker, Rachael, Mani, Madhav, Carthew, Richard W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340504/
https://www.ncbi.nlm.nih.gov/pubmed/32568073
http://dx.doi.org/10.7554/eLife.56076