Crystal structures and calorimetry reveal catalytically relevant binding mode of coproporphyrin and coproheme in coproporphyrin ferrochelatase

Coproporphyrin ferrochelatases (CpfCs, EC 4.99.1.9) insert ferrous iron into coproporphyrin III yielding coproheme. CpfCs are utilized by prokaryotic, mainly monoderm (Gram-positive) bacteria within the recently detected coproporphyrin-dependent (CPD) heme biosynthesis pathway. Here, we present a co...

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Detalles Bibliográficos
Autores principales: Hofbauer, Stefan, Helm, Johannes, Obinger, Christian, Djinović-Carugo, Kristina, Furtmüller, Paul G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340540/
https://www.ncbi.nlm.nih.gov/pubmed/31794133
http://dx.doi.org/10.1111/febs.15164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340540/
https://www.ncbi.nlm.nih.gov/pubmed/31794133
http://dx.doi.org/10.1111/febs.15164

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