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Calbindin Deficits May Underlie Dissociable Effects of 5-HT(6) and mGlu(7) Antagonists on Glutamate and Cognition in a Dual-Hit Neurodevelopmental Model for Schizophrenia
Despite several compounds entering clinical trials for the negative and cognitive symptoms of schizophrenia, few have progressed beyond phase III. This is partly attributed to a need for improved preclinical models, to understand disease and enable predictive evaluation of novel therapeutics. To thi...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340678/ https://www.ncbi.nlm.nih.gov/pubmed/32533466 http://dx.doi.org/10.1007/s12035-020-01938-x |